The most common version of Mirapex is covered by 74% of insurance plans at a co-pay of $60. Il contribue à améliorer le contrôle des muscles et. It is in the anti-parkinsonian class of drugs. Obsessive Compulsive Behaviors have been reported by hundreds of users with dangerous consequences, what begins as a drug of benefit can turn into a drug of ruin, beware. Mirapex (pramipexole) for Restless Legs Syndrome "My wife has suffered from RLS for 8 years. has put me on neurtron500 mg a day. Pramipexole is used to treat Parkinson disease. Neuropsychology Clinic. Some people taking the medicine in MIRAPEX ER have had car accidents because they fell asleep. Dopamine agonists are drugs that activate certain types of cells in your brain. Using a medication such as Mirapex helps to relieve symptoms. MiraLAX is the #1 Doctor recommended laxative, providing effective and predictable relief for occasional constipation. 5mg daily • Pramipexole (Mirapex®) is available in 0. 650-723-6469. You may report side effects to FDA at 1-800-FDA. pramipexole + codeine avoid combo if antitussive use; otherwise monitor resp. Immediate-release tablet (Mirapex) is approved to treat either Parkinson symptoms or RLS. Your doctor may adjust your dose as needed. MIRAPEX tablets contain pramipexole, a nonergot dopamine agonist. As your trusted partner, we deliver business-driven solutions that include the scalability and support needed to power growth. Augmentation is when a certain type of drug causes your RLS symptoms to worsen in severity. 00, which is 88% off the. Sinemet (carbidopa-levodopa) is a combination of an inhibitor of aromatic amino acid decarboxylation and an aromatic amino acid used to treat Parkinson symptoms such as. hallucinations. The risk is increased if you have low blood levels of magnesium or potassium, which can occur with. It works for RLS, but just be aware of this rare but devastating side effect. So his answer is take more meds. and adolescents. Drugs. In some cases, patients using the NEUPRO Patch experienced localized redness, swelling, or itching where the patch was applied. 650-723-7181. Atorvastatin, B12 5000mcg,Clonazepam . To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Mirapex; Mirapex ER; Descriptions. La mirtazapina MIRTAPAX es un antagonista presináptico de los receptores alfa2 activo a nivel central, que aumenta la neurotransmisión serotoninérgica y adrenérgica central. , overnight) switch to pramipexole (Mirapex®) 0. Central Cali [831] Sep 8, 2009. Abnormal behavior in the litter box (crying, digging, uncleanliness) Loss of appetite. Dizziness, lightheadedness, or fainting, especially when standing up suddenly from a sitting/lying position. I'm on 2mg for 16 years of mirapex. MIRAPEX ER tablets are taken once daily, with or without food ()Tablets must be swallowed whole and must not be chewed, crushed, or divided ()Starting dose is 0. It is an extended-release tablet that can be taken once a day. Five other anti-tremor drugs also showed elevated risks but Mirapex accounted for 58% of the reports. 5 out of 10 from a total of 100 reviews for the treatment of Restless Legs Syndrome. Classified as a dopamine receptor agonist, pramipexole elicits partial or full agonism upon D3 receptors, D2 receptors (2L/2S), and D4 receptors. 7 out of 10 from a total of 69 ratings on Drugs. Impulse-control behavior: intense urges for certain behaviors (e. I feel in my heart this may help. All of the dopamine agonists, ropinirole, pramipexole, and Neupro, share many of the same risks, so choosing one over another may not avoid a side effect. For. There are 7 disease interactions with Paxlovid (nirmatrelvir / ritonavir) which include: liver dysfunction. Mirapex ER (pramipexole dihydrochloride) is an approved, extended-release oral therapy used to ease symptoms in people with Parkinson’s disease. Took for the first time a few hours ago. Ropinirole. Contraindications. In the meantime I made an appointment with a sleep doc at University of Florida. 375 mg/day PO initially; if necessary, may be increased every 5-7 days, first to 0. Pramipexole (Mirapex) is a non-ergot selective dopamine receptor agonist that has been used since 1997 for the treatment of idiopathic Parkinson's disease. When pramiprexole is used to treat Parkinson's disease, the regular tablet is usually taken three times a day and the extended-release tablet is usually taken once daily. Mirapex Interactions. . 5 mg is around $118 for a supply of 30 tablets, depending on the pharmacy you visit. The classic mirepoix is made up of onion, carrot, and. Patients taking Metamucil capsules should drink eight ounces of liquid with each dose 2. When this is the case, your lungs aren’t. MIRAPEX ER may cause serious side effects, including: falling asleep during normal daily activities. Taking Mirapex with food may help prevent stomach upset. MIRAPEX (pramipexole dihydrochloride - tablet;oral) Manufacturer: BOEHRINGER INGELHEIM Approval date: July 1, 1997traZODone polyethylene glycol 3350. The powder dissolves in any beverage. They are typically well tolerated, and adverse effects (e. Side effects, drug interactions, patient safety, storage, and dosage information should be reviewed prior to taking this medication. Mirapex Settlement — $8. It is available in brand and generic versions. unusual tiredness or weakness. I have been taking Mirapex for approximately 12 years. While levodopa is converted in the brain into dopamine, dopamine agonists mimic the effects of dopamine without having to be converted. Dosis. El pramipexol también se usa para tratar el síndrome de piernas inquietas (RLS [en inglés]; una afección que causa molestias en las piernas y una fuerte necesidad de moverlas, especialmente de noche y cuando está sentado o acostado). When pramiprexole is used to treat restless legs syndrome, the regular tablet is. Metamucil, because it is a fiber supplement, has other purposes and health benefits than Miralax. 223. I got down to 1 mg of Mirapex, but my body has become so accustomed to the medication that I can't. 5mg Tablet ER is used in the treatment of Parkinson's disease,Restless leg syndrome. Of the total drug interactions, 4 are major, 241 are moderate, and 9 are minor. hemophilia. Composición. unusual tiredness or weakness. Be careful going up and down stairs. The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study revealed that more than 1 in 3 outpatients with major depressive disorder will not achieve symptomatic remission despite several attempts at monotherapy, augmentation, and/or combination. A psychotropic drug is a drug that affects behavior, mood, thoughts, or perception. References . That works for most people. 5 mg, Mirapax 2 1. com. I was waiting to see if my body got accustomed to Mirapex but. It has done nothing to allow me to feel joy upon completing a project. Mirapex has an average rating of 7. Pramipexole is also used to treat restless legs. It employs 11-20 people and has $1M-$5M of revenue. 62% of reviewers reported a positive effect, while 23% reported a negative effect. The amount available is gabapentin 300 mg capsules. Who is Mirapax. 5 mg/d was used. Based on your current dosing, you might need to slowly decrease the dose to around 6 mg of Requip per day before being able to switch to 3 mg of Mirapax. by Sherri Woodbridge August 17, 2017. Miralax can be used on a daily basis for the treatment or prophylaxis of constipation, but is also used in higher amounts for bowel prep prior to colonoscopies. com Mobile Apps. 3 in placebo-treated patients. This means they help you move feces through your bowels. Many of pramipexole’s side effects begin early in treatment, particularly the most common side effects, such as nausea, dizziness, headache, trouble sleeping, strange dreams, fatigue, dry mouth, and increased urination. changes in emotions or moods. I have no problems falling asleep say around 11 pm but I wake at 2 or 3 am and I cannot fall asleep again. Mirapex was awesome but the dose had to be increased every few months. You should avoid or limit the use of alcohol while being treated with these medications. It is a dopamine agonist that directly stimulates nerves in the brain that are not naturally being stimulated by dopamine. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. 4 years ago. Cells throughout your nervous system have receptors, which are like locks, on their surfaces. 05 of Mirapex and 2 - 5mg of Melatonin each evening before bedtime. 3. Pramipexole has an average rating of 6. This activity describes pramipexole's indications, action, and contraindications as a valuable agent in managing parkinsonism and restless leg syndrome. PROPIEDADES FARMACOLÓGICAS: Grupo farmacoterapéutico: Agonista dopaminérgico, código ATC: N04BC05. They hurt constansly and I am up most nights all night. Purpose: A hyperosmolar formulation of Miralax-Gatorade (238g of PEG-3350 in 64oz of Gatorade) has gained wide acceptance for bowel prep prior to colonoscopy. 1 General Dosing Considerations . Pramipexole immediate release (IR) administered three times daily (TID) is an efficacious and generally well-tolerated treatment for PD. Side effects of Mirapex and Neurontin that are similar include dizziness, drowsiness, blurred or double vision, and memory problems ( amnesia or forgetfulness). Learn about dosage, side effects, uses, and more. Enter the imprint code that appears on the pill. That resolves when the Mirapex is reduced or discontinued. Obsessive Compulsive Behaviors have been reported by hundreds of users with dangerous consequences, what begins as a drug of benefit can turn into a drug of ruin, beware. Feel tired but legs still restless. meds. Ropinirole. This medication contains pramipexole. There are dozens, both prescription and commonly misused. It's good that you recognize the issue. Pramipexole dihydrochloride extended- release tablets are taken once daily, with or without food ()Tablets must be swallowed whole and must not be chewed, crushed, or divided ()Starting dose is 0. Simens is suing all the companies. You say your main symptoms are buzzing and twitching and these 24/7. Pramipexole(Mirapex) generic is a dopamine agonist, prescribed for Parkinson's disease and Restless Leg Syndrome. 58% of reviewers reported a positive effect, while 31% reported a negative effect. 0 mg, 4. Lack of energy. Classified as a dopamine receptor agonist, pramipexole elicits partial or full agonism upon D3 receptors, D2 receptors (2L/2S), and D4 receptors. Pramipexole was approved for use in the United States in 1997 for the therapy of symptomatic Parkinson disease. MiraLax works by holding water within the colon to soften the stool and increasing the number of bowel movements to relieve constipation. Augmentation most often occurs within six. Call Today for a FREE Confidential Case Review Toll-Free 24/7 (866) 920-0753. Applies to: trazodone and MiraLAX (polyethylene glycol 3350) TraZODone can cause an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. Metamucil should be mixed with eight ounces of a beverage and can be taken up to three times a day 2. We've worked and are working on alternative treatments using supplements/exercise but so far all we've been able to do is drop her dose from 3 to 1 tablet every evening. Find everything you need to know about Pramipexole (Mirapex), including what it is used for, warnings, reviews, side effects, and interactions. The most common agonists are Mirapex and Requip. Pramipexole Dihydrochloride is a drug prescribed for treatment of Parkinson’s Disease and Restless Leg Syndrome. 8 in the patients treated with MIRAPEX tablets, regardless of assigned dose group, and 0. 5mg tablets with a recommended dosing frequency of 3 times daily. sleep problems (insomnia), unusual dreams. There are 254 drugs known to interact with Mirapex (pramipexole), along with 4 disease interactions, and 1 alcohol/food interaction. 5 mg of pramipexole, and 179 with placebo. Inactive ingredients consist of mannitol. It is not intended for long-term use, and should not be used as a regular supplement for bowel regularity. 2 Million (June 2008) Mirapex is a prescription drug used to treat the symptoms of Parkinson’s disease. trouble sleeping. 59% of reviewers reported a positive experience, while 25% reported a negative experience. CALL NOW! 1-800-968-7529. Do not take Mirapex or Mirapex ER if you are allergic to pramipexole or any ingredients contained in this drug. 3 in placebo-treated patients. For Parkinson disease: Adults—At first, 0. 5 mg per day. Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. Be careful going up and down stairs. 66% of reviewers reported a positive experience, while 19% reported a negative experience. Applies to: Mirapex (pramipexole) and Cymbalta (duloxetine) Using pramipexole together with DULoxetine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. MIRAPEX ER may cause you to fall asleep while you are doing daily activities such as driving, talking with other people, or eating. Much like natural dopamine, Mirapex binds to dopamine receptors and stimulates them. This is not a complete list of side effects and others may occur. Mirapex ®), компанії «Boehringer Ingelheim », режим дозування та ціна в аптеках поруч | КомпендіумThe AME should first consider the safety impact of the underlying condition being treated and then determine the frequency, duration, and side effects (if any) of the medication being used. Interestingly, pramipexole also appears to modify mitochondrial. Miralax is an osmotic laxative, binding water to the stool for easier passage. 2. Common interactions include vomiting among females, and fatigue among males. Dizziness, lightheadedness, or fainting, especially when standing up suddenly from a sitting/lying position. Gabapentin, Gabapentin enacarbil, pregabalin. This is apparently where following withdrawal of dopamine agonist drugs, like Mirapex, the brain doesn’t re-start producing its own dopamine. drowsiness. The immediate release version of pramipexole (Mirapex) is released into the body soon after taking it, and takes about two hours to kick in. In a randomized trial in patients with restless legs syndrome, pregabalin provided significantly improved treatment outcomes as compared with placebo. Read more about Mirapex®, drugs, which can help compensate for the absence of the neurotransmitter dopamine in patients with Parkinson's disease. By inhibiting CYP1A2, the concentration of ropinirole could rise and cause toxicity. The impulse control disorder is the Pramipexole but hopefully it will settle once you're off it completely. g. I thought my days of taking Mirapex and becoming sexual were numbered while waiting for pharm. A mirepoix is a combination of finely chopped aromatic vegetables that gives a subtle background flavor to dishes such as soups, stews, sauces, and braises. In contrast, Metamucil is a fiber supplement that can be used daily to help maintain regularity and promote digestive health. My Dr. It works by holding water in the stool to soften the stool and increases the number of bowel movements. Pramipexole is a dopamine agonist that works on the nervous system to help treat the symptoms of Parkinson disease. INDICACIONES: Depresión. We use cookies to give you the best possible experience on our website. Have you a replacement drug - you need one normally to perform 2 actions - 1) help the withdrawal from the DA and, 2) replace the Mirapex with something that is going to work on RLS. This means they help you move feces through your bowels. MiraLAX has an average rating of 7. com. We would like to show you a description here but the site won’t allow us. MIRAPEX tablets (1. Why is ropinirole being discontinued? The FDA announcement indicates that the discontinuation of ropinirole tablets is due to a “business decision” made by pharmaceutical manufacturer GlaxoSmithKline. . View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Usually, if you have taken Requip for a while now, then the usual recommendation for you to slowly decrease the dose of Requip. Gabapentin can lead to respiratory depression in people with reduced lung function due to COPD. If you are taking Mirapex ER, you should not take Mirapex. It may increase the action of certain chemical receptors in the brain. 5mg , Multivitamin 200mcg. It may be used alone or in combination with other medicines (eg, levodopa). It is more popular than comparable drugs. Pramipexole alleviated the anticipated pain I felt whenever I was faced with any task. Depression is one of the most common mental health conditions, affecting about 5% of the world’s population. The most common version of Mirapex is covered by 74% of insurance plans at a co-pay of $60. In some people, pramipexole may cause a sudden onset of sleep, even during the daytime. Some of the mental and muscle problems are delayed side effects. Example: L484 Select the the pill color (optional). I suffer from restless leg syndrome mainly in the feet. 2 MIRAPEX® PR: 0. Pramipexole is a prescription drug. Each is known for causing addictive behaviors such as sexual addiction and gambling. 2 out of 10 from a total of 120 ratings on Drugs. A total of 719 participants received daily treatment, 182 with 300 mg of pregabalin, 178 with 0. Pramipexole (Mirapex) and ropinirole (Requip) should be used to treat patients with moderate to severe RLS. Pramipexole, sold under the brand Mirapex among others, is medication used to treat Parkinson's disease and restless legs syndrome . It is based on pramipexole dihydrochloride and homatropine methylbromide; hydrocodone bitartrate (the active ingredients of Mirapex and Hydrocodone compound, respectively), and Mirapex and Hydrocodone compound (the brand names). MIRAPEX ER may cause you to fall asleep while you are doing daily activities such as driving, talking with other people, or eating. a: A modern and minimalist nickname that emphasizes the dot between the “M” and “i” in Mira’s name. However, the dose of 1. Created for people with ongoing healthcare needs but benefits everyone. Then my legs started hurting and and I can't sleep. Step 2 Remove yourself from situations where you feel tempted to gamble. Brand names: Mirapex, Mirapex ER. I was. Puede ser usado como monoterapia o en combinación con levodopa. Pramipexole (brand names: Mirapex, Mirapex ER) is a dopamine agonist used to treat symptoms of Parkinson's disease and restless legs syndrome (RLS). Based on efficacy and tolerability, dosages may be. They hurt constansly and I am up most nights all night. sexual thoughts,expressions (I am 69) thinking words in my head that I would never use, undressing people in my mind,. We've worked and are working on alternative treatments using supplements/exercise but so far all we've been able to do is drop her dose from 3 to 1 tablet every evening. It is also used to treat symptoms of moderate to severe restless leg syndrome. Metamucil (psyllium fiber) is contraindicated (i. Pramipexole is a member of the dopaminergic antiparkinsonism agents drug class and is commonly used for Parkinson's Disease, Periodic Limb Movement Disorder, Restless Legs Syndrome, and others. In Parkinson's disease it. Uses. Its empirical formula is C 10 H 17 N 3 S • 2HCl • H 2 O, and its molecular weight is 302. 75 mg, 1 mg, 1. 75 mg/day; not to exceed 4. MiraLax is an osmotic laxative that is used to treat occasional constipation or irregular bowel movements. Mirapex ® [package insert]. Our. Pramipexole. Pramipex 0. Pramipexole is typically initiated in low. Avoid driving or operating machinery while using Mirapex. Las dosis efectivas de mantenimiento oscilan entre 15mg y 45mg por día. This is a common issue with drugs like Mirapex. MECANISMO DE ACCIÓN: Los trastornos depresivos aparecen cuando la neurotransmisión en las sinapsis del sistema límbico-hipocampo se enlentece, a consecuencia de una disminución en la síntesis y liberación de los neurotransmisores propios de las neuronas de estas estructuras. Much like natural dopamine, Mirapex binds to dopamine receptors and stimulates them. For oral dosage form (tablets): For Parkinson disease: Adults—At first, 0. Read More. Mirapex 3mg Tablet ER is used in the treatment of Parkinson's disease,Restless leg syndrome. Il s'utilise dans le traitement des signes et des symptômes de la maladie de Parkinson. A lower dose can be maintained if that is preferred. Requip and Mirapex are also used to treat restless legs syndrome (RLS). Over a period of 12. If a further dose increase is necessary, the daily dose should be increased by 0. If you asking how long does miralax stay in your system then i must say Miralax stays in the system for about four to five hours. Miralax is an osmotic laxative that contains polyethylene glycol. Periodic Limb Movement. changes in vision. Do not drink alcohol while you are taking Mirapex. Dosis de MIAPAX. 650-723-7181. If a significant interruption in therapy with MIRAPEX ER tablets has occurred, re-titration of therapy may be warranted. Pramipexole se usa en el tratamiento de los síntomas de la enfermedad de Parkinson (rigidez, temblores, espasmos musculares, y pobre control muscular). Get medical help right away, if you have any of the symptoms listed above. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. 1)Mirapex (Pramipexole) is a moderately priced drug used to treat symptoms of Parkinson's disease. La dosis de eszopiclona debe ser personalizada. In Parkinson's disease it may be used alone or together with levodopa. Mirapex (pramipexole), a common treatment for Parkinson’s disease, is believed to work by boosting the action of whatever dopamine is available, which is low in people with Parkinson’s. It's one of the first-choice options for Parkinson's disease (PD) to relieve symptoms. Parkinson disease is a progressive neurodegenerative disorder with significant morbidity and mortality. This is not a complete list of. 75 mg per day and then by 0. Official answer. Body weight changes occur during the clinical course of Parkinson's disease (PD) and with surgical treatment, but the effect of dopaminergic treatment on weight is unknown. You can use the study as a second opinion to make health care decisions. It works by acting like dopamine, a substance in your body that helps manage movements and coordination. 1. MIRAPEX ER tablets must be swallowed whole and must not be chewed, crushed, or divided. The company is headquartered in Dobříš, Central Bohemia, Czech Republic. Mirapex Alternatives Compared. Side Effects. Clinics for Mirapex®. We discuss uses, dangers, and more. SO. Metamucil is a bulk-forming laxative that contains fiber and works by adding. estimate a target dose of Mirapex 1. It is now labeled for the treatment of. Unbearable at times. Juno EMR - Launch of our new User Interface! We have officially launched our newest User Interface! With the Juno UI, there are a lot of modern features included that will help. google rls and see if you can find any other ideas. 375 milligram (mg) once a day. com. Mainly just anhedonia. Mirapax (pramipexole) side effects - hyper sexual almost ended in divorce! My husband was diagnosed at the age of 35 with early onset. Pramipexole también se usa para el tratamiento del síndrome de la piernas inquietas (RLS, por sus siglas en Inglés). 25, 0. MIRAPEX tablets, for oral administration, contain 0. In addition, augmentation (worsening) rates. Like Abilify, Mirapex is a dopamine agonist. Comparing Mirapex vs Requip. 25 mg. 78 Obory, Dobříš, Central Bohemia, 263 01, Czech Republic. It took Scholarly Articles On The Use Of Mirapax To Treat Low Libido so long to see the Fang family. . View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. We have previously reported a case series of patients with severe hyponatremia (serum sodium < 130 mEq/l). МІРАПЕКС ПД таблетки пролонгованої дії — повна інструкція по застосуванню препарату (лат. Studies and Lawsuits Point Fingers at the Parkinson’s Drug, MIRAPEX. Brand names: Mirapex ER. 2 DOSAGE AND ADMINISTRATION . It has done nothing to enhance other emotions. Here's a list of meds- what I WAS taking and what I'm now taking:Then -81 mg aspirin, 20 mg. 5 mg per day. These include hallucinations, memory impairment,. 0 tablet er) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. Summary for Dopamine agonist. It has done nothing to enhance other emotions. See also Warning section. Los pacientes que ya se encontraban tomando MIRAPEX ® comprimidos pueden cambiar a MIRAPEX ® comprimidos de liberación prolongada de administración nocturna, con la misma dosis. Official answer. The way it works can be confused with Metamucil but the difference is that Miralax does not swell up and. Be sure to check with your doctor before taking any action regarding your health. In terms of side effects, it sometimes can cause. 25 mg of pramipexole, 180 with 0. daughter-Advocate. 2 The. Depressive disorders are common, costly, and often chronic or recurrent. Applies to: Sinemet (carbidopa / levodopa) and Mirapex (pramipexole) Using levodopa together with pramipexole may increase the effects of levodopa. In fact my mirapex prescription now comes with a warning to contact my Dr. Pramipexole has an average rating of 6. unless I take about 1/3 the dose with a tooooooon of water. He is also a trophy husband, everything you would want from a man. Depressive disorders are common, costly, and often chronic or recurrent. With me, it is the depression that has hit the hardest. 125 Tablet is used in the treatment of Parkinson's disease,Restless leg syndrome. Mirapex may be taken with or without food. It is taken by mouth. Pramipexole alleviated the anticipated pain I felt whenever I was faced with any task. 75 mg/day and then by increments of 0. Mirapex ER (pramipexole) is a member of the dopaminergic antiparkinsonism agents drug class and is commonly used for Parkinson's Disease. Interestingly, pramipexole also appears to modify mitochondrial. pramipexole DULoxetine. Mirapex Interactions. 00-$80. En asociación con levodopa: 1,5 a 4,5mg/día divididos en 3 tomas diarias, junto con alrededor de 800mg de levodopa por día, teniendo en cuenta que en estudios clínicos se observó que la introducción de pramipexol induce una reducción aproximada del 27%. MIRAPEX tablets are taken orally, with or without food. Ropinirole is a dopamine agonist that's used to treat Parkinson's disease (PD) and restless legs syndrome (RLS) in adults. Nephrology and Dialysis 44 years experience. Sinemet (carbidopa / levodopa) is a combination medication made up of carbidopa and levodopa. If a significant interruption in therapy with MIRAPEX ER tablets has occurred, re-titration of therapy may be warranted. 5 mg/day). The brand name therapy was developed by Boehringer Ingelheim and approved in the. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. I have been on Mirapax for years.